Meta-languages are vital to the development and usage of formal systems, and yet the nature of meta-languages and associated notions require clarification. Here we attempt to provide a clear definition of the requirements for a language to be a meta-language, together with consideration of issues of proof theory, model theory and interpreters for such a language.

Jaswal & Akhtar provide several quotes ostensibly from people with autism but obtained via the discredited techniques of Facilitated Communication and the Rapid Prompting Method, and they do not acknowledge the use of these techniques. As a result, their argument is substantially less convincing than they assert, and the article lacks transparency.

Randomized controlled trial trial designs exist on an explanatory-pragmatic spectrum, depending on the degree to which a study aims to address a question of efficacy or effectiveness. As conceptualized by Schwartz and Lellouch in 1967, an explanatory approach to trial design emphasizes hypothesis testing about the mechanisms of action of treatments under ideal conditions, whereas a pragmatic approach emphasizes testing effectiveness of two or more available treatments in real-world conditions. Interest in, and the number of, pragmatic trials has grown substantially (...) in recent years, with increased recognition by funders and stakeholders worldwide of the need for credible evidence to inform clinical decision-making. This increase has been accompanied by the onset of learning healthcare systems, as well as an increasing focus on patient-oriented research. However, pragmatic trials have ethical challenges that have not yet been identified or adequately characterized. The present study aims to explore the views of key stakeholders with respect to ethical issues raised by the design and conduct of pragmatic trials. It is embedded within a large, four-year project that seeks to develop guidance for the ethical design and conduct of pragmatic trials. As a first step, this study will address important gaps in the current empirical literature with respect to identifying a comprehensive range of ethical issues arising from the design and conduct of pragmatic trials. By opening up a broad range of topics for consideration within our parallel ethical analysis, we will extend the current debate, which has largely emphasized issues of consent, to the range of ethical considerations that may flow from specific design choices. Semi-structured interviews with key stakeholders, across multiple jurisdictions, identified based on their known experience and/or expertise with pragmatic trials. We expect that the study outputs will be of interest to a wide range of knowledge users including trialists, ethicists, research ethics committees, journal editors, regulators, healthcare policymakers, research funders and patient groups. All publications will adhere to the Tri-Agency Open Access Policy on Publications. (shrink)

The nature of moral action versus moral judgment has been extensively debated in numerous disciplines. We introduce Virtual Reality (VR) moral paradigms examining the action individuals take in a high emotionally arousing, direct action-focused, moral scenario. In two studies involving qualitatively different populations, we found a greater endorsement of utilitarian responses–killing one in order to save many others–when action was required in moral virtual dilemmas compared to their judgment counterparts. Heart rate in virtual moral dilemmas was significantly increased when compared (...) to both judgment counterparts and control virtual tasks. Our research suggests that moral action may be viewed as an independent construct to moral judgment, with VR methods delivering new prospects for investigating and assessing moral behaviour. (shrink)

Causal mediation analysis is complicated with multiple effect definitions that require different sets of assumptions for identification. This article provides a systematic explanation of such assumptions. We define five potential outcome types whose means are involved in various effect definitions. We tackle their mean/distribution’s identification, starting with the one that requires the weakest assumptions and gradually building up to the one that requires the strongest assumptions. This presentation shows clearly why an assumption is required for one estimand and not another, (...) and provides a succinct table from which an applied researcher could pick out the assumptions required for identifying the causal effects they target. Using a running example, the article illustrates the assembling and consideration of identifying assumptions for a range of causal contrasts. For several that are commonly encountered in the literature, this exercise clarifies that identification requires weaker assumptions than those often stated in the literature. This attention to the details also draws attention to the differences in the positivity assumption for different estimands, with practical implications. Clarity on the identifying assumptions of these various estimands will help researchers conduct appropriate mediation analyses and interpret the results with appropriate caution given the plausibility of the assumptions. (shrink)

Last year, we reported a new mechanism of DNA replication in mammals. It occurs inside mitochondria and entails the use of processed transcripts, termed bootlaces, which hybridize with the displaced parental strand as the replication fork advances. Here we discuss possible reasons why such an unusual mechanism of DNA replication might have evolved. The bootlace mechanism can minimize the occurrence and impact of single‐strand breaks that would otherwise threaten genome stability. Furthermore, by providing an implicit mismatch recognition system, it should (...) limit the occurrence of replication‐dependent deletions and insertions, and defend against invading elements. Such a mechanism may also limit attempts to manipulate the mammalian mitochondrial genome. (shrink)

The article reviews recent developments in England in the law of necessity as a defence to crime and calls for its further extension. It argues that the defence of necessity presents the criminal law with difficult questions of competing values and the ordering of harms. English law has taken a nuanced position on the respective roles of the courts and the legislature in the ordering of harms, although the development of the law has been pragmatic rather than coherently theorised. The (...) law has granted necessity some scope as an exculpatory principle in the law of general defences, but it has also respected the primacy of the legislature as the legitimate arbiter of many of the competitions of value that necessity throws up. The recognition of necessity has not been in the form of a single unified defence of that name. Rather it has taken the form of a number of defences, based on a principle of necessity, but with different nomenclature and different rationales. This approach to necessity is defended as right in terms of principle and policy. Any further development of necessity as a general defence should be restricted to two contexts, namely those of emergencies, and of conflicts of duty, where a danger of death or serious injury is present. (shrink)

A growing literature testifies to the persistence of place as an incorrigible aspect of human experience, identity, and morality. Place is a common ground for thought and action, a community of experienced particulars that avoids solipsism and universalism. It draws us into the philosophy of the ordinary, into familiarity as a form of knowledge, into the wisdom of proximity. Each of these essays offers a philosophy of place, and reminds us that such philosophies ultimately decide how we make, use, and (...) understand places, whether as accidents, instruments, or fields of care. (shrink)

Recent advances in virtual technologies have allowed the investigation of simulated moral actions in aversive moral dilemmas. Previous studies have employed diverse populations in order to explore these actions, with little research considering the significance of occupation on moral decision-making. For the first time, in this study we have investigated simulated moral actions in Virtual Reality made by professionally trained paramedics and fire service incident commanders who are frequently faced with and must respond to moral dilemmas. We found that specially (...) trained individuals showed distinct empathic and related personality trait scores and that these declined with years of experience working in the profession. Supporting the theory that these professionals develop resilience in moral conflict, reduced emotional arousal was observed during virtual simulations of a distressing dilemma. Furthermore, trained professionals demonstrated less regret following the execution of a moral action in virtual reality when compared to untrained control populations. We showed that, contrary to previous research, trained individuals made the same moral judgments and moral actions as untrained individuals, though showing less arousal and regret. In the face of increasing concerns regarding empathy decline in healthcare professionals, we suggest that the nature of this decline is complex and likely reflects the development of a necessary emotional resilience to distressing events. (shrink)

© Ginn et al. 2016.The indexing methods currently used for serial femtosecond crystallography were originally developed for experiments in which crystals are rotated in the X-ray beam, providing significant three-dimensional information. On the other hand, shots from both X-ray free-electron lasers and serial synchrotron crystallography experiments are still images, in which the few three-dimensional data available arise only from the curvature of the Ewald sphere. Traditional synchrotron crystallography methods are thus less well suited to still image data processing. Here, a (...) new indexing method is presented with the aim of maximizing information use from a still image given the known unit-cell dimensions and space group. Efficacy for cubic, hexagonal and orthorhombic space groups is shown, and for those showing some evidence of diffraction the indexing rate ranged from 90% to 151%. Here, the indexing rate refers to the number of lattices indexed per image. (shrink)

Intellectual humility is a hot topic. One of the key questions the literature is exploring is definitional: What is intellectual humility? In their recent paper, “Intellectual Humility: Owning our Limitations,” Dennis Whitcomb, Heather Battaly, Jason Baehr, and Daniel Howard-Snyder have proposed an answer: Intellectual humility is “proper attentiveness to, and owning of, one’s intellectual limitations”. I highlight some limitations of the limitations-owning account of intellectual humility. And in conclusion, I suggest that ultimately these are not limitations that any viable (...) account of intellectual humility should own and that Whitcomb et al. should revise their view accordingly. (shrink)

Historians and philosophers of science have furnished a wide array of theoretical-historiographical terms to emphasize the discontinuities among different systems of knowledge. Some of the most famous include Thomas Kuhn’s “paradigm”, Michel Foucault’s “episteme”, and the notion of “styles of reasoning” more recently developed by Ian Hacking and Arnold Davidson. This paper takes up this theoretical-historiographical thread by assessing the values and limitations of the notion of “style” for the historical and philosophical study of science. Specifically, reflecting on various methodological (...) and theoretical concerns prompted by sexuality, translation, and East Asian studies, this paper argues that the heretofore ways in which historians and philosophers of science have used the notion of “style” are severely restricted in terms of its mere applicability to the intellectual history of Western science. The particular example of the translation of “homosexuality” into Chinese during the May Fourth era reveals that the notion of “style” has the potential of carrying a much more dynamic conceptual weight, as when used in “styles of argumentation”. The paper also engages briefly with the historiography of scientific “national styles” and ends with some concluding remarks on the limitations of “social histories from below” and the under appreciated importance of “epistemological histories of possibilities”. (shrink)

This book studies the work of John Stuart Mill in order to answer the question: what is political theory? Looking at what political theorists have written about this subject leads to the conclusion that they have different ways of defining political theory, resulting in different readings of political theory. In defense of this argument, Reading Mill includes three different readings of the works of John Stuart Mill and identifies a fourth type of political theorist unlikely to read Mill. (...) When it comes to the question with which the book began, the only answer is that political theory is not one but four possible practices. This means that there are four different ways of reading a political theorist and reading political theory. The book calls for political theorists to recognize the value of their different ways of understanding political theory and, as a result, to tolerate their differences where they cannot celebrate them. (shrink)

This paper examines the question of whether scientific realism is committed to the inevitability of science or is consistent with claims of the contingency of science. In order to address this question, a general characterization of the position of scientific realism is presented. It is then argued that scientific realism has no evident implications with regard to the inevitability of science. A historical case study is presented in which contingency plays a significant role, and the appropriate realist response to this (...) case study is indicated. Finally, it is argued that, when conjoined with a reliabilist theory of method, realism does have implications for the inevitability of science.Keywords: Inevitability; Contingency; Scientific realism; Reliabilism; Ian Hacking. (shrink)

The paper discusses the version of entity realism presented by Ian Hacking in his book, Representing and Intervening. Hacking holds that an ontological form of scientific realism, entity realism, may be defended on the basis of experimental practices which involve the manipulation of unobservable entities. There is much to be said in favour of the entity realist position that Hacking defends, especially the pragmatist orientation of his approach to realism. But there are problems with the position. The paper explores two (...) issues that reflect negatively on Hacking’s version of the entity realist position. The first issue relates to the role of description in fixing the reference of theoretical terms. The second issue relates to Hacking’s claim that the argument for entity realism based on experiment is a different kind of argument from the standard argument for scientific realism based on the success of science. (shrink)

Family medicine has grown as a specialty from its early days of general practice. It was established as a Board Certified specialty in 1969. This growth and maturation can be traced in the philosophy of family medicine as articulated by Edmund D. Pellegrino, M.D. Long before it was popular to do so, Pellegrino supported the development of family medicine. In this essay I examine the development of Pellegrino's philosophical thought about family practice, and contrast it to other thinkers like Ian (...) McWhinney, Kerr White, Walter Spitzer, Donald Ransom, and Hebert Vandervoort. The arguments focus on whether the goals of family medicine and family practice (possibly two distinct entities) can be articulated, especially considering the definitional problems of family and community. I conclude by echoing Pellegrino's hope that family medicine can contribute a fresh alternative to isolated, individualistic and technological thinking in medicine. (shrink)

This is a sequel to my paper, ‘What is Scientific Realism?’, which appeared in an earlier issue of this journal (Sankey, 2000a). A number of papers by other authors on topics relating to scientific realism have followed in subsequent issues. In this paper I revisit some of the themes developed in my earlier paper in the light of these later papers. I begin by restating the key ideas of the earlier paper. Next, I mention a number of afterthoughts which I (...) have had since the appearance of the paper. I then offer some comments on three of these subsequent papers. I hope these comments advance the discussion by clarifying and developing a number of key points. (shrink)

Jerome Bruner is one of the grand figures of psychology. From his role as a founder of the cognitive revolution in the 1950s to his recent advocacy of cultural psychology, Bruner's influence has been dramatic and far-reaching. Such is the breadth of his vision that Bruner's work has inspired thinkers in many of the major areas of psychology and has had a powerful impact on adjacent disciplines. His writings on language acquisition, culture and education are of profound and enduring importance. (...) Focusing on the dominant themes of language, culture and self, this volume provides a comprehensive exploration of Bruner's fertile ideas and a considered appraisal of his legacy. With a distinguished list of contributors including Jerome Bruner himself, the result is an outstanding volume of interest to students and scholars in psychology, philosophy, cognitive science, anthropology, linguistics, and education. Among the contributors are Judy Dunn, Howard Gardner, Clifford Geertz, Rom Harré, David Olson, Edward Reed, Talbot Taylor, Michael Tomasello, and John Shotter. The volume is framed by an editorial introduction that considers the distinctively philosophical dimensions of Bruner's thought, and a final chapter by Bruner himself in which he re-examines prominent themes in his work in light of issues raised by the contributors. The volume will be invaluable to students and researchers in the fields of psychology, cognitive science, education, and the philosophy of mind. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Fiery Test of Critique: A Reading of Kant's Dialectic by Ian ProopsStephen HowardIan Proops. The Fiery Test of Critique: A Reading of Kant's Dialectic. Oxford: Oxford University Press, 2021. Pp. 512. Hardback, $105.00.Ian Proops's book is a substantial contribution to the thriving field of Anglophone scholarship on the Transcendental Dialectic of Kant's Critique of Pure Reason. Across five hundred pages, Proops examines the whole of the Dialectic. (...) The book is divided into three parts, following the disciplines of previous special metaphysics with which Kant critically engages in the Dialectic: rational psychology, cosmology, and theology. Discussions of transcendental illusion and the regulative use of ideas of reason are slotted into the rational psychology and theology parts, respectively.Methodologically, Proops aims to take a middle course between historical and reconstructive approaches (31–32). In historical and reconstructive modes alike, though, Proops is primarily concerned with accurately presenting and rigorously evaluating Kant's arguments in the Dialectic. These arguments come in two forms: either those of the imagined rational psychologist, cosmologist, or theologian, whom Kant ventriloquizes in order to reveal their errors; or those arguments that Kant makes in his own voice. The Fiery Test of Critique distinguishes itself from existing studies through the detail and care with which these arguments are scrutinized. Specialists will find numerous illuminating exegeses and links to a wide range of Kant's published and unpublished writings. Proops does not hesitate to identify where, in his view, Kant's arguments fail (or where those of Kant's ventriloquized metaphysicians fail in a way Kant does not intend), but he endeavors to interpret charitably and to make his own evaluative criteria explicit.The wide-ranging introduction to the book offers intriguing reflections on a metaphor Kant uses for his critique of pure reason: a "fiery test" (8; A 406/B 433). This test, Proops suggests, is best understood not as a religious ordeal by fire but as a "metallurgical assay": the testing of a coin or an ore to determine its precious metal content (9–10). This means that the test of critique "is not pass-fail" (12). Kantian critique identifies some precious metal to be retained alongside the dross (the base-metal bearer) to be discarded. The "gold" [End Page 525] and "silver" found by Kant's fiery test are, Proops contends, respectively the indirect proof of transcendental idealism that emerges from the Antinomy chapter, and the doctrinal beliefs in God and an afterlife that remain after the Paralogism and Ideal (13, 453–54).This application of Kant's metaphor indicates how far Proops diverges from the dismissive views of older Anglo-American studies of the Dialectic (the paradigm being Bennett's Kant's Dialectic [Cambridge: Cambridge University Press, 1974]). Proops's opening questions and goals show that he aims to clarify the precise character of the dogmatic metaphysical claims criticized by Kant, and to identify what of this previous tradition Kant considers worth saving and why (2–7). This focus on the positive contribution of the Dialectic to Kant's philosophy—an approach Proops shares with other recent commentators—is very welcome.For all his illuminating discussion of Kant's Feuerprobe imagery, Proops neglects to note that Kant does not simply identify worthwhile aspects of previous special metaphysics. Rather, the philosophical findings that Proops takes to be the precious results of the critical test are significantly developed in Kant's hands. That is, no pre-Kantian rational cosmologist claims that their debates provide an indirect proof of transcendental idealism (of course). Neither do pre-Kantian rational psychologists or theologians make Kant's move of conceiving of God and the immortal soul as matters of doctrinal belief, where the latter is an epistemic attitude distinct from knowledge and cognition. In the cases that Proops highlights, then, the relevant image seems to be not only a metallurgical test but also an alchemical transformation of previous metaphysical doctrines into positive "critical" results.The parts of the book on the Paralogisms and the Ideal, on which Proops has previously published, will no doubt stimulate further detailed debate among specialists. I leave these debates aside to consider the part of the... (shrink)

Constructing a particular nation, that of early modern England, is seen here as a series of theatrical performances. Shakespeare’s work is taken as a series of thought experiments. Some, like The Merchant of Venice, are reassuring that threatening circumstances and innovatory social practices are capable of being overcome or assimilated from the unknown to the known. Some, like King Lear and Hamlet, ponder the consequences of a failure to discover a resolution. Some writers have argued that England was historically quite (...) early in beginning to conceive of itself as a nation, rather than as a population of possibly heterogeneous regions subject to a dynasty, a state of affairs summarized in the by now clichéd remark attributed to the Sun King, “L’Etat, c’est moi”. For Shakespeare, if not for all of his contemporaries, the Englishman is a bit slow-witted, owing to his fondness for beef and red wine, but he is distinguishable from others and provides material for the second pieces of theater I look at. If there could be an Englishman, his experience with the absolutist pretensions of the Stuart monarchy allowed there to be a free-born Englishman (and, actually, Englishwoman). The two crucial battles of the English civil war, Marston Moor and Naseby, followed by the Army Debates of 1647–1649 form the stage for an at least aspiring egalitarianism we now know as the rights of man, or the rights of the civic person. (shrink)

This book includes sections on brightness and light, eye movements and perception, and perception of orientation and self-motion.

In the late Middle Ages the philosopher and mystic Meister Eckhart preached that to know the truth you must be the truth. But how to be the truth? Eckhart's answer comes in the form of an imperative: release yourself, let be. Only then will you be able to understand that the deepest meaning of being is releasement. Only then will you become who you truly are. This book interprets Eckhart's Latin and Middle High German writings under the banner of an (...) imperative of releasement, and then shows how the twentieth-century thinker Martin Heidegger creatively appropriates this idea at several stages of his career. Heidegger had a lifelong fascination with Eckhart, referring to him as "the old master of letters and life." Drawing on archival material and Heidegger's marginalia in his personal copies of Eckhart's writings, Moore argues that Eckhart was one of the most important figures in Heidegger's philosophy. This book also contains previously unpublished documents by Heidegger on Eckhart, as well as the first English translation of Nishitani Keiji's essay "Nietzsche's Zarathustra and Meister Eckhart," which he initially gave as a presentation in one of Heidegger's classes in 1938. (shrink)

Ethics in nursing: continuity and change -- Cultural issues, methods and approaches to nursing ethics -- Nursing ethics: what do we mean by 'ethics'? -- Becoming a nurse and member of the profession -- Power and responsibility in nursing practice and management -- Professional responsibility and accountability in nursing -- Classical areas of controversy in nursing and biomedical ethics -- Direct responsibility in nurse/patient relationships -- Conflicting demands in nursing groups of patients -- Ethics in healthcare management: research, evaluation and (...) performance management -- The political ethics of healthcare: health policies and resource allocation -- Corporate ethics in healthcare: strategic planning and ethical policy development -- Making moral decisions and being able to justify our actions -- The relevance of moral theory: justifying our ethical policies. (shrink)

In this book of essays, he argues that morality cannot be defined solely by rational and universal principles; instead, a major place must be found for changing and conflicting ideals, values peculiar to specific times and cultures.

Published in 1982 by CUP (pb. 2009) it discusses the forms of materialism then current, including Davidson, early Rorty, but concentrating on Smart and Armstrong, and arguing that central state materialism fails to give a better 'occurrent' account of conscious states than does behaviourism/functionalism, as Armstrong claims. The book starts with a version of the 'knowledge argument' and ends with a chapter claiming that our conception of matter/the physical is more problematic than our conception of mind.

Infallibilism is the view that a belief cannot be at once warranted and false. In this essay we assess three nonpartisan arguments for infallibilism, arguments that do not depend on a prior commitment to some substantive theory of warrant. Three premises, one from each argument, are most significant: if a belief can be at once warranted and false, then the Gettier Problem cannot be solved; if a belief can be at once warranted and false, then its warrant can be transferred (...) to an accidentally true belief; if a belief can be at once warranted and false, then it can be warranted and accidentally true. We argue that each of these is either false or no more plausible than its denial. Along the way, we offer a solution to the Gettier Problem that is compatible with fallibilism. (shrink)

[This book offers] compilation of examples from TV, newspapers, magazines, advertisements, and our nation's political dialogue.

In this book, Stuart Hampshire argues that no individual and no modern society can avoid conflicts between incompatible moral interests.